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The big problem with the 7-0-1 combo is it works in earlier rounds but later it is not very effective. I'd say a pretty safe strat is in beginning use the 7-0-1 then around round 4 pull out the 5-4-1 and transition it back to 3-2-1 combo and save nitro for semis as well.
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Depends on the bracket. One may have to use nitro earlier or if they're lucky they can save it for finals.