I haven't done pixel art in a few months so this is pretty bad, it is suposed to be a clown mask with smudged makeup, made it on paintbrush, don't tell me to use less colors. 
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I know you don't wanna hear it, but I used less colors haha
If you are making things for graal, a black outline is always best. Gives it a pop
Also what I did was define a light source, I also made the eyes a focus point of the graphic by mixing light and dark shades together on the point of focus. Also with the lips, no one has a straight line of lips with one color, I included an upper and bottom, I also altered the shading in that reason to give a smear look.